The Smallest Workers in Regenerative Medicine: Stem Cell-Derived Exosomes

Extracellular vesicles (EVs) are secreted by cells into the extracellular space, first discovered in 1967 as platelet dust. In recent years, idea that EVs can treat various diseases has emerged studies to understand these vesicles' origin and biological functions. According their size, biogenesis, content, release pathways function, have three main subtypes: microvesicle (MV), exosome (EX) apoptotic body. found all body fluids, including urine, plasma, physiological fluids such bronchial lavage. addition, it is many cell types dendritic cells, B T-cells, mast tumour sperm. This literature article reviewed using stem cell-derived numerous clinical preclinical studies.